The IDF confirmed that two Israelis were killed in the shooting attack, and that its forces were conducting sweeps in the area in an attempt to capture the perpetrators.
"It was a very difficult sight," said MDA paramedic Boaz Malka. "We saw a car in the middle of the road with a man in his thirties next to it with wounds to his upper body, and a woman in her thirties inside the car also seriously wounded in her upper body. They were without signs of life, and unfortunately we had to declare them dead at the scene."
A Hamas spokesman praised the attack by the "brave resistance," calling the murderous act "heroic," and vowing to continue the struggle against Israel. The organization call for its members to carry out more attacks against Israel.
The Popular Resistance Committees also "blessed" the attack, saying it was a natural reaction to "Israeli crimes."
Knesset opposition chairman Isaac Herzog, said on his Twitter account: "The murder in Samaria which immediately put an end to the holiday jubilation, is abhorrent and extremely painful. I send my condolences to the family and the community at large which is hurting and feeling such pain. We must let the IDF and security forces act quickly and steadfastly in order to capture these murders."
The UN's Special Coordinator for the Middle East Peace Process, Nickolay Mladenov, said, “I condemn this evening’s shooting attack on an Israeli civilian vehicle which resulted in the death of two people and injuries to their four children in the occupied West Bank.There is nothing heroic about the killing of civilians. The perpetrators of this violent act must be brought to justice."
President Reuven Rivlin also condemned the attack, saying: "Tonight, bloodthirsty murderers claimed the lives of a mother and a father, leaving their young children orphaned. The heart breaks at the magnitude of such cruelty and hatred...